MEASUREMENT OF PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME IN SUDANESE SICKLE CELL ANEMIA PATIENTS IN KHARTOUM STATE

  • Type: Project
  • Department: Medical and Health Science
  • Project ID: MHS0160
  • Access Fee: ₦5,000 ($14)
  • Pages: 84 Pages
  • Format: Microsoft Word
  • Views: 498
  • Report This work

For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

Abstract This is a case control study aimed to measure levels of, Prothombin time (PT), activated partial Thromboplastin time (APTT), platelet count in patients with homozygous sickle cell disease (HbSS), sickle cell trait (HbAS) and normal controls (HbAA). The study period from August to October 2019, in Khartoum State in the Sickle Cell Clinic of Gaffer Ibn Auf Children Specialized Hospital and Al-ribat University hospital. The study population comprises two groups of children in different agegroups and gender. The first group of 50 individuals included are the children who are known to have sickle cell anemia (HbSS 41) and (HbAS 9). The second group of 50 individuals included are normal-healthy (HbAA) as a control group. Venous blood sample was collected into tri sodium citrate (9:1) and centrifuged at 4000 rpm for 10 min to obtain plts poor plasma for coagulation study. PT and APTT were measured using (DIA Timer 2) and platelets count obtained from records. The data collected using questionnaire, and analyzed using Statistical Package Social Science programme (Version 20). Students T test and One way ANOVA test were used to compare between means. P. value significant when ≤0.05. PT (seconds) mean and SD were 15.4±1.7, 14.6±0.8 in cases and healthy subjects respectively, P. values were 0.000 and APTT (seconds) mean and SD were 40.8±4.9, 37.1±3.3 in cases and healthy subjects respectively, P. values were 0.000. Both PT and APTT were high in SCD patient compare to control group. Mean level of platelets count (cumm) were 389±204, 281±71 in the cases and controls respectively, P. value was 0.01. Statistically there was significant deferens between cases group and control group in platelets count (cumm).increased platelet count in cases.

MEASUREMENT OF PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME IN SUDANESE SICKLE CELL ANEMIA PATIENTS IN KHARTOUM STATE
For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

Share This
  • Type: Project
  • Department: Medical and Health Science
  • Project ID: MHS0160
  • Access Fee: ₦5,000 ($14)
  • Pages: 84 Pages
  • Format: Microsoft Word
  • Views: 498
Payment Instruction
Bank payment for Nigerians, Make a payment of ₦ 5,000 to

Bank GTBANK
gtbank
Account Name Obiaks Business Venture
Account Number 0211074565

Bitcoin: Make a payment of 0.0005 to

Bitcoin(Btc)

btc wallet
Copy to clipboard Copy text

500
Leave a comment...

    Details

    Type Project
    Department Medical and Health Science
    Project ID MHS0160
    Fee ₦5,000 ($14)
    No of Pages 84 Pages
    Format Microsoft Word

    Related Works

                                                                                    Abstract Sickle cell disease is the commonest genetic disease worldwide and includes disorders affecting the structure, function or production of haemoglobin, that afflicts a great number of... Continue Reading
    Abstract Sickle cell disease is the commonest genetic disease worldwide and includes disorders affecting the structure, function or production of haemoglobin, that afflicts a great number of people in this... Continue Reading
    Abstract The aim of this study is to evaluate of the diffusion magnetic resonance imaging with clinical findings for brain stroke patients in Khartoum state, to evaluate the doctor's experience about the diffusion weighted imaging for brain stroke, measure the accuracy of diffusion weighted imaging in detection brain stroke, compare the DWI... Continue Reading
    Abstract This was analytical study conducted during the period from January to April 2017, to determine the antimicrobial activity of Azadirachta indica leaves methanolic extract against different bacteria isolated from urinary tract infection. A total of 130 urine samples were collected from patients with Urinary tract infection. These specimens... Continue Reading
                                                                                   Abstract Sickle cell disease (SCD) is an autosomal recessively inherited disorder and one of the most common genetic conditions worldwide. Over 300 million people have sickle cell traits... Continue Reading
                                                                                   Abstract Sickle cell disease (SCD) is an autosomal recessively inherited disorder and one of the most common genetic conditions worldwide. Over 300 million people have sickle cell traits... Continue Reading
    ABSTRACT Health care is a necessity and a basic human need. Households or individuals often derived various strategies to cope with large health expenditure. Sickle-cell Anaemia is the most frequent haemoglobin disorder and one of the world’s greatest cause of morbidity and mortality mostly in sub-Saharan Africa. This research work title the... Continue Reading
    ABSTRACT Sickle cell disease is a hereditary condition that result from a single glutamic acid to valine substitution of position 6 of the beta globin polypeptide chain. It is inherited as an autosomal recessive trait. This glutamic aicd being subsituted by valine is characterized by drastic reduction in... Continue Reading
    ABSTRACT Health care is a necessity and a basic human need. Households or individuals often derived various strategies to cope with large health expenditure. Sickle-cell Anaemia is the most frequent haemoglobin disorder and one of the world’s greatest cause of morbidity and mortality mostly in sub-Saharan Africa. This research work title the... Continue Reading
    ABSTRACT The rationale for this project is to design a public health communication strategy for campaign on sickle cell anemia in Ghana. This project has been necessitated by the alarming rate at which the condition is occurring. It is generally estimated that 2% of children born in Ghana each year have a form of the sickle cell disease. This... Continue Reading
    Call Us
    whatsappWhatsApp Us